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Page 1
Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis.
Whitehead A, Krause FN, Moran A, MacCannell ADV, Scragg JL, McNally BD, Boateng E, Murfitt SA, Virtue S, Wright J, Garnham J, Davies GR, Dodgson J, Schneider JE, Murray AJ, Church C, Vidal-Puig A, Witte KK, Griffin JL, Roberts LD. Whitehead A, et al. Among authors: krause fn. Nat Commun. 2021 Mar 26;12(1):1905. doi: 10.1038/s41467-021-22272-3. Nat Commun. 2021. PMID: 33772024 Free PMC article.
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function.
Asowata EO, Romoli S, Sargeant R, Tan JY, Hoffmann S, Huang MM, Mahbubani KT, Krause FN, Jachimowicz D, Agren R, Koulman A, Jenkins B, Musial B, Griffin JL, Soderberg M, Ling S, Hansen PBL, Saeb-Parsy K, Woollard KJ. Asowata EO, et al. Among authors: krause fn. Kidney Int. 2024 Feb 29:S0085-2538(24)00168-6. doi: 10.1016/j.kint.2024.01.041. Online ahead of print. Kidney Int. 2024. PMID: 38431215 Free article.
Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress.
O'Brien KA, McNally BD, Sowton AP, Murgia A, Armitage J, Thomas LW, Krause FN, Maddalena LA, Francis I, Kavanagh S, Williams DP, Ashcroft M, Griffin JL, Lyon JJ, Murray AJ. O'Brien KA, et al. Among authors: krause fn. BMC Biol. 2021 Dec 15;19(1):265. doi: 10.1186/s12915-021-01192-0. BMC Biol. 2021. PMID: 34911556 Free PMC article.
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination.
McMurran CE, Guzman de la Fuente A, Penalva R, Ben Menachem-Zidon O, Dombrowski Y, Falconer J, Gonzalez GA, Zhao C, Krause FN, Young AMH, Griffin JL, Jones CA, Hollins C, Heimesaat MM, Fitzgerald DC, Franklin RJM. McMurran CE, et al. Among authors: krause fn. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25311-25321. doi: 10.1073/pnas.1905787116. Epub 2019 Nov 18. Proc Natl Acad Sci U S A. 2019. PMID: 31740610 Free PMC article.
Propionate functions as a feeding state-dependent regulatory metabolite to counter proinflammatory signaling linked to nutrient load and obesity.
Han K, Meadows AM, Rodman MJ, Russo AC, Sharma R, Singh K, Hassanzadeh S, Dagur PK, Huffstutler RD, Krause FN, Griffin JL, Baumer Y, Powell-Wiley TM, Sack MN. Han K, et al. Among authors: krause fn. J Leukoc Biol. 2024 Mar 29;115(4):738-749. doi: 10.1093/jleuko/qiae006. J Leukoc Biol. 2024. PMID: 38207130 Free PMC article.